Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ntsr1tm2Dgen
Name:	neurotensin receptor 1; targeted mutation 1, Deltagen
MGI ID:	MGI:3761722
Synonyms:	NTR1-
Gene:	Ntsr1  Location: Chr2:180141769-180186772 bp, + strand  Genetic Position: Chr2, 103.04 cM, cytoband H1-H4
Alliance:	Ntsr1tm2Dgen page

Germline Transmission:	Earliest citation of germline transmission: J:126020
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A null allele was create by deleting 457 nucleotides including the initiator methionine at nucleotide position 8 and inserting of a neo cassette. RT-PCR and immunohistochemistry were used to confirm the absence of a transcript. (J:126020)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntsr1 Mutation:	31 strains or lines available

Original:	J:126020 Pettibone DJ, et al., The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin. J Pharmacol Exp Ther. 2002 Jan;300(1):305-13
All:	2 reference(s)