Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Paqr3tm1Ychn
Name:	progestin and adipoQ receptor family member III; targeted mutation 1, Yan Chen
MGI ID:	MGI:3757569
Synonyms:	RKTG-
Gene:	Paqr3  Location: Chr5:97230188-97259455 bp, - strand  Genetic Position: Chr5, 47.29 cM
Alliance:	Paqr3tm1Ychn page

Germline Transmission:	Earliest citation of germline transmission: J:124964
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced by a neomycin selection cassette that caused a downstream frameshift in sequences encoding the transmembrane domains of this protein. RT-PCR analysis of liver RNA indicated that a truncated transcript is produced from this allele. (J:124964)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Paqr3 Mutation:	22 strains or lines available

Original:	J:124964 Feng L, et al., Spatial regulation of Raf kinase signaling by RKTG. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14348-53
All:	7 reference(s)