Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bchetm1Loc
Name:	butyrylcholinesterase; targeted mutation 1, Oksana Lockridge
MGI ID:	MGI:3723049
Synonyms:	BChE-, BChE KO
Gene:	Bche  Location: Chr3:73543141-73615748 bp, - strand  Genetic Position: Chr3, 33.61 cM, cytoband E3
Alliance:	Bchetm1Loc page

Germline Transmission:	Earliest citation of germline transmission: J:124975
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: 891bp of the gene is replaced with a neomycin selection cassette, including 485bp from the 3' end of intron 1 and 406bp from the 5' end of exon 2. The region encoding the entire signal peptide, the translation start site, and the first 102 amino acids of the mature protein is deleted. (J:124975)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Bche Mutation:	32 strains or lines available

Original:	J:124975 Li B, et al., Production of the butyrylcholinesterase knockout mouse. J Mol Neurosci. 2006;30(1-2):193-5
All:	11 reference(s)