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Catsper4tm1Wyan
Targeted Allele Detail
Summary
Symbol: Catsper4tm1Wyan
Name: cation channel, sperm associated 4; targeted mutation 1, Wei Yan
MGI ID: MGI:3720685
Synonyms: Catsper4-
Gene: Catsper4  Location: Chr4:133939281-133954694 bp, - strand  Genetic Position: Chr4, 66.5 cM
Alliance: Catsper4tm1Wyan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:124054
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-3 were replaced with the Pgk-HPRT minigene cassette. Northern blot confirmed ablation of the transcript. (J:124054)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Catsper4 Mutation:  26 strains or lines available
References
Original:  J:124054 Jin J, et al., Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse. Biol Reprod. 2007 Jul;77(1):37-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory