Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il25tm1Anjm
Name:	interleukin 25; targeted mutation 1, Andrew N J McKenzie
MGI ID:	MGI:3720374
Synonyms:	Il25-
Gene:	Il25  Location: Chr14:55170152-55173294 bp, + strand  Genetic Position: Chr14, 28.0 cM
Alliance:	Il25tm1Anjm page

Germline Transmission:	Earliest citation of germline transmission: J:123748
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to insert a neomycin selection cassette into exon 2 to replace the nucleotides encoding amino acids 22-86. RT-PCR confirmed absence of transcript in mutant mast cells. (J:123748)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il25 Mutation:	14 strains or lines available

Original:	J:123748 Fallon PG, et al., Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med. 2006 Apr 17;203(4):1105-16
All:	18 reference(s)