Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Angptl4tm1Lex
Name:	angiopoietin-like 4; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:3716688
Synonyms:	Angptl4-
Gene:	Angptl4  Location: Chr17:33993874-34000549 bp, - strand  Genetic Position: Chr17, 17.98 cM
Alliance:	Angptl4tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:122968
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A targeting vector was designed to replace exons 2 and 3 with a neomycin resistance gene. (J:122968)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angptl4 Mutation:	31 strains or lines available

Original:	J:122968 Desai U, et al., Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11766-71
All:	5 reference(s)