Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Itgb1bp1tm1Ref
Name:	integrin beta 1 binding protein 1; targeted mutation 1, Feinhard Fassler
MGI ID:	MGI:3716519
Synonyms:	Icap1-
Gene:	Itgb1bp1  Location: Chr12:21317247-21336285 bp, - strand  Genetic Position: Chr12, 8.3 cM
Alliance:	Itgb1bp1tm1Ref page

Germline Transmission:	Earliest citation of germline transmission: J:122741
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector containing a lacZ-pgk-neo cassette replaced part of exon 2 and all of exon 3. Northern and Western blot analyses confirmed absence of transcript and protein, respectively, in mutants. (J:122741)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itgb1bp1 Mutation:	14 strains or lines available

Original:	J:122741 Bouvard D, et al., Defective osteoblast function in ICAP-1-deficient mice. Development. 2007 Jul;134(14):2615-25
All:	4 reference(s)