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Tnip3tm1Rds
Targeted Allele Detail
Summary
Symbol: Tnip3tm1Rds
Name: TNFAIP3 interacting protein 3; targeted mutation 1, Robert D Schreiber
MGI ID: MGI:3716211
Synonyms: ABIN-3-null, Tnip3-
Gene: Tnip3  Location: Chr6:65567382-65611024 bp, + strand  Genetic Position: Chr6, 30.26 cM
Alliance: Tnip3tm1Rds page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122758
Parent Cell Line:  MC50 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-5 were replaced by a floxed neo, which was subsequently removed via cre mediated recombination. Absence of protein was confirmed in mutants. (J:122758)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnip3 Mutation:  21 strains or lines available
References
Original:  J:122758 Weaver BK, et al., ABIN-3: a molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions. Mol Cell Biol. 2007 Jul;27(13):4603-16
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory