Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bmp4tm3.2Blh
Name:	bone morphogenetic protein 4; targeted mutation 3.2, Brigid L Hogan
MGI ID:	MGI:3715255
Synonyms:	Bmp4delta-lacZ
Gene:	Bmp4  Location: Chr14:46620982-46628126 bp, - strand  Genetic Position: Chr14, 23.95 cM
Alliance:	Bmp4tm3.2Blh page

Germline Transmission:	Earliest citation of germline transmission: J:122530
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Exons 3 and 4 were removed by cre-mediated recombination to create a loss of function allele. (J:122530)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp4 Mutation:	21 strains or lines available

Original:	J:122530 Michos O, et al., Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development. 2007 Jul;134(13):2397-405
All:	1 reference(s)