Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Commd1tm1Bvds
Name:	COMM domain containing 1; targeted mutation 1, Bart van de Sluis
MGI ID:	MGI:3714157
Synonyms:	Commd1-
Gene:	Commd1  Location: Chr11:22849728-22934539 bp, - strand  Genetic Position: Chr11, 14.22 cM
Alliance:	Commd1tm1Bvds page

Germline Transmission:	Earliest citation of germline transmission: J:122208
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced with a neo cassette creating a null allele. Absence of protein product was confirmed with western blot analysis. (J:122208)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	20 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Commd1 Mutation:	31 strains or lines available

Original:	J:122208 van de Sluis B, et al., Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice. Mol Cell Biol. 2007 Jun;27(11):4142-56
All:	1 reference(s)