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C1galt1tm1.2Rpmc
Targeted Allele Detail
Summary
Symbol: C1galt1tm1.2Rpmc
Name: core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; targeted mutation 2, Rodger P McEver
MGI ID: MGI:3714051
Synonyms: T-syn-
Gene: C1galt1  Location: Chr6:7845224-7872042 bp, + strand  Genetic Position: Chr6, 3.37 cM, cytoband A1
Alliance: C1galt1tm1.2Rpmc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122012
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exons 1 and 2 are deleted via cre-mediated recombination to form a null allele. (J:122012)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any C1galt1 Mutation:  24 strains or lines available
References
Original:  J:122012 Williams SA, et al., Fertilization in mouse does not require terminal galactose or N-acetylglucosamine on the zona pellucida glycans. J Cell Sci. 2007 Apr 15;120(Pt 8):1341-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory