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Plxnb1tm1Rkun
Targeted Allele Detail
Summary
Symbol: Plxnb1tm1Rkun
Name: plexin B1; targeted mutation 1, Rohini Kuner
MGI ID: MGI:3713703
Synonyms: Plxnb1-
Gene: Plxnb1  Location: Chr9:108924457-108948985 bp, + strand  Genetic Position: Chr9, 59.63 cM
Alliance: Plxnb1tm1Rkun page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121970
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre-mediated recombination was used to remove exons 12 through 17 creating a null allele. The absence of protein product was confirmed by western blot analysis. (J:121970)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plxnb1 Mutation:  107 strains or lines available
References
Original:  J:121970 Deng S, et al., Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J Neurosci. 2007 Jun 6;27(23):6333-47
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory