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Irf4tm1.1Rdf
Targeted Allele Detail
Summary
Symbol: Irf4tm1.1Rdf
Name: interferon regulatory factor 4; targeted mutation 1.1, Riccardo Dalla-Favera
MGI ID: MGI:3712352
Synonyms: Irf4-
Gene: Irf4  Location: Chr13:30933209-30950959 bp, + strand  Genetic Position: Chr13, 13.28 cM, cytoband A3.3
Alliance: Irf4tm1.1Rdf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112643
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe null allele was generated by crossing mice carrying the floxed Irf4 allele with Flpe-expressing mice to delete exons 1 and 2 and the EGFP sequence. (J:112643)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Irf4 Mutation:  27 strains or lines available
References
Original:  J:112643 Klein U, et al., Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol. 2006 Jul;7(7):773-82
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory