Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mpp4tm1Tili
Name:	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4); targeted mutation 1, Tiansen Li
MGI ID:	MGI:3711731
Synonyms:	Mpp4-
Gene:	Mpp4  Location: Chr1:59160094-59202548 bp, - strand  Genetic Position: Chr1, 29.2 cM
Alliance:	Mpp4tm1Tili page

Germline Transmission:	Earliest citation of germline transmission: J:121771
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2, which contains the translational start codon, was replaced with a neomycin resistance cassette. Immunoblot confirmed absence of protein in mutants. (J:121771)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mpp4 Mutation:	42 strains or lines available

Original:	J:121771 Yang J, et al., Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals. Hum Mol Genet. 2007 May 1;16(9):1017-29
All:	1 reference(s)