Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cxcr6tm1Lex
Name:	C-X-C motif chemokine receptor 6; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:3710094
Synonyms:	Cxcr6-
Gene:	Cxcr6  Location: Chr9:123635542-123640819 bp, + strand  Genetic Position: Chr9, 74.57 cM, cytoband F
Alliance:	Cxcr6tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:120952
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exon 2 with a lacZ/neo. RT-PCR confirmed absence of wild-type transcript in mutants. (J:120952)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cxcr6 Mutation:	30 strains or lines available

Original:	J:120952 Sasai K, et al., Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor. Cancer Res. 2007 Apr 15;67(8):3871-7
All:	1 reference(s)