Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ddb2tm1Vri
Name:	damage specific DNA binding protein 2; targeted mutation 1, Harry Vrieling
MGI ID:	MGI:3707217
Synonyms:	Ddb2-
Gene:	Ddb2  Location: Chr2:91041917-91067327 bp, - strand  Genetic Position: Chr2, 50.56 cM, cytoband E1
Alliance:	Ddb2tm1Vri page

Germline Transmission:	Earliest citation of germline transmission: J:103406
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exons 4-7 were replaced with a puromycin resistance cassette. (J:103406)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddb2 Mutation:	38 strains or lines available

Original:	J:103406 Alekseev S, et al., Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation. Cancer Res. 2005 Nov 15;65(22):10298-306
All:	2 reference(s)