Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ddb1tm1.1Spg
Name:	damage specific DNA binding protein 1; targeted mutation 1.1, Stephen P Goff
MGI ID:	MGI:3698414
Synonyms:	DDB1delta
Gene:	Ddb1  Location: Chr19:10582961-10607186 bp, + strand  Genetic Position: Chr19, 6.66 cM, cytoband centromere
Alliance:	Ddb1tm1.1Spg page

Germline Transmission:	Earliest citation of germline transmission: J:117820
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Germline expression of cre recombinase resulted in the excision of exon 5. (J:117820)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddb1 Mutation:	33 strains or lines available

Original:	J:117820 Cang Y, et al., Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells. Cell. 2006 Dec 1;127(5):929-40
All:	1 reference(s)