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Surf1tm2Zev
Targeted Allele Detail
Summary
Symbol: Surf1tm2Zev
Name: surfeit gene 1; targeted mutation 2, Massimo Zeviani
MGI ID: MGI:3698399
Synonyms: SurfloxP-NEO-loxP
Gene: Surf1  Location: Chr2:26803393-26806542 bp, - strand  Genetic Position: Chr2, 19.1 cM
Alliance: Surf1tm2Zev page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117871
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A floxed neomycin resistance cassette was inserted into exon 7. (J:117871)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Surf1 Mutation:  14 strains or lines available
References
Original:  J:117871 Dell'agnello C, et al., Increased longevity and refractoriness to Ca2+-dependent neurodegeneration in Surf1 knockout mice. Hum Mol Genet. 2007 Feb 15;16(4):431-44
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory