Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Camkk1tm1Tch
Name:	calcium/calmodulin-dependent protein kinase kinase 1, alpha; targeted mutation 1, Talal A Chatila
MGI ID:	MGI:3697455
Gene:	Camkk1  Location: Chr11:72909834-72932899 bp, + strand  Genetic Position: Chr11, 45.12 cM
Alliance:	Camkk1tm1Tch page

Germline Transmission:	Earliest citation of germline transmission: J:117630
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced exons 2 through 5. Immunoblot confirmed absence of protein in mutants. (J:117630)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Camkk1 Mutation:	20 strains or lines available

Original:	J:117630 Blaeser F, et al., Long-term memory deficits in Pavlovian fear conditioning in Ca2+/calmodulin kinase kinase alpha-deficient mice. Mol Cell Biol. 2006 Dec;26(23):9105-15
All:	4 reference(s)