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Mad1l1tm1.1Ktj
Targeted Allele Detail
Summary
Symbol: Mad1l1tm1.1Ktj
Name: MAD1 mitotic arrest deficient 1-like 1; targeted mutation 1.1, Kuan-Teh Jeang
MGI ID: MGI:3697324
Synonyms: Mad1-
Gene: Mad1l1  Location: Chr5:139994444-140307307 bp, - strand  Genetic Position: Chr5, 78.82 cM
Alliance: Mad1l1tm1.1Ktj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117337
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 10 was removed via cre-mediated recombination in the germline. (J:117337)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Mad1l1tm1.1Ktj
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mad1l1 Mutation:  65 strains or lines available
References
Original:  J:117337 Iwanaga Y, et al., Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice. Cancer Res. 2007 Jan 1;67(1):160-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory