Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rdh12tm1Kpal
Name:	retinol dehydrogenase 12; targeted mutation 1, Krzysztof Palczewski
MGI ID:	MGI:3696994
Synonyms:	Rdh12-
Gene:	Rdh12  Location: Chr12:79255687-79269438 bp, + strand  Genetic Position: Chr12, 35.51 cM, cytoband D2
Alliance:	Rdh12tm1Kpal page

Germline Transmission:	Earliest citation of germline transmission: J:117483
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exons 1, 2 and 3 with a neo cassette. Immunoblot failed to detect protein in mutant retina extracts. (J:117483)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rdh12 Mutation:	17 strains or lines available

Original:	J:117483 Maeda A, et al., Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice. J Biol Chem. 2006 Dec 8;281(49):37697-704
All:	7 reference(s)