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Acvr1tm1.1Vk
Targeted Allele Detail
Summary
Symbol: Acvr1tm1.1Vk
Name: activin A receptor, type 1; targeted mutation 1.1, Vesa Kaartinen
MGI ID: MGI:3696672
Synonyms: Acvr1fx(exon7), Alk2delta7
Gene: Acvr1  Location: Chr2:58336450-58456840 bp, - strand  Genetic Position: Chr2, 33.05 cM
Alliance: Acvr1tm1.1Vk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73148
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 7 was removed via cre mediated recombination in Acvr1tm1Vk mutants. (J:73148)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
In Structures Affected by this Mutation: 31 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acvr1 Mutation:  44 strains or lines available
References
Original:  J:73148 Kaartinen V, et al., Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo. Genesis. 2001 Nov;31(3):126-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory