Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sytl2tm1Mitf
Name:	synaptotagmin-like 2; targeted mutation 1, Mitsunori Fukuda
MGI ID:	MGI:3693881
Synonyms:	Slp2-a-
Gene:	Sytl2  Location: Chr7:89951460-90059927 bp, + strand  Genetic Position: Chr7, 50.54 cM
Alliance:	Sytl2tm1Mitf page

Germline Transmission:	Earliest citation of germline transmission: J:116278
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced the entire protein-coding region in exon 1. Western blot confirmed absence of protein in mutant stomachs. (J:116278)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Sytl2 Mutation:	62 strains or lines available

Original:	J:116278 Saegusa C, et al., Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells. Genes Cells. 2006 Jun;11(6):623-31
All:	1 reference(s)