Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Jag1tm2.1Grid
Name:	jagged 1; targeted mutation 2.1, Tom Gridley
MGI ID:	MGI:3693129
Synonyms:	Jag1del2
Gene:	Jag1  Location: Chr2:136923371-136958440 bp, - strand
Alliance:	Jag1tm2.1Grid page

Germline Transmission:	Earliest citation of germline transmission: J:115783
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Jag1tm2Grid mice were crossed to Tg(Zp3-cre)93Knw mice. Heterozygous females carrying the transgene were crossed to wild-type males to produce mice heterozygous for Jag1 with exon 4 deleted. (J:115783)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jag1 Mutation:	76 strains or lines available

Original:	J:115783 Kiernan AE, et al., The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet. 2006 Jan;2(1):e4
All:	1 reference(s)