Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Agertm1.1Hyam
Name:	advanced glycosylation end product-specific receptor; targeted mutation 1.1, Hiroshi Yamamoto
MGI ID:	MGI:3692766
Synonyms:	Rage-
Gene:	Ager  Location: Chr17:34816836-34819910 bp, + strand  Genetic Position: Chr17, 18.18 cM
Alliance:	Agertm1.1Hyam page

Germline Transmission:	Earliest citation of germline transmission: J:116040
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 1 and 2 were removed via transient cre-mediated recombination. Western blot of mutant lung and kidney confirm absence of protein in mutants. (J:116040)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ager Mutation:	28 strains or lines available

Original:	J:116040 Myint KM, et al., RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin. Diabetes. 2006 Sep;55(9):2510-22
All:	36 reference(s)