Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bmpertm1Ysas
Name:	BMP-binding endothelial regulator; targeted mutation 1, Yoshiki Sasai
MGI ID:	MGI:3691854
Synonyms:	Cv2-
Gene:	Bmper  Location: Chr9:23134372-23396496 bp, + strand  Genetic Position: Chr9, 9.55 cM, cytoband A4
Alliance:	Bmpertm1Ysas page

Germline Transmission:	Earliest citation of germline transmission: J:115338
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The first methionine was replaced in-frame with that of tau-lacZ with a floxed neo. RT-PCR failed to detect wild-type transcript in mutants. (J:115338)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	21 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bmper Mutation:	47 strains or lines available

Original:	J:115338 Ikeya M, et al., Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development. 2006 Nov;133(22):4463-73
All:	3 reference(s)