Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Taldo1tm1Perl
Name:	transaldolase 1; targeted mutation 1, Andras Perl
MGI ID:	MGI:3690444
Synonyms:	TAL-
Gene:	Taldo1  Location: Chr7:140972112-140982881 bp, + strand  Genetic Position: Chr7, 86.73 cM, cytoband F3-F4
Alliance:	Taldo1tm1Perl page

Germline Transmission:	Earliest citation of germline transmission: J:114691
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced sequence spanning from exon 4 to intron 4, encoding amino acids 138-153. Western blot confirmed that wild-type protein was not detected in mutants. (J:114691)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taldo1 Mutation:	11 strains or lines available

Original:	J:114691 Perl A, et al., Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14813-8
All:	4 reference(s)