Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pdcd1lg2tm1Shr
Name:	programmed cell death 1 ligand 2; targeted mutation 1, Arlene H Sharpe
MGI ID:	MGI:3688152
Synonyms:	PD-L2-
Gene:	Pdcd1lg2  Location: Chr19:29388319-29448561 bp, + strand  Genetic Position: Chr19, 23.93 cM, cytoband C2-C3
Alliance:	Pdcd1lg2tm1Shr page

Germline Transmission:	Earliest citation of germline transmission: J:113851
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A targeting vector replaced the IgV exon with the hygromycin resistance gene. (J:113851)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdcd1lg2 Mutation:	23 strains or lines available

Original:	J:113851 Liang SC, et al., PD-L1 and PD-L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis. Eur J Immunol. 2006 Jan;36(1):58-64
All:	5 reference(s)