About   Help   FAQ
Pth1rtm1Abas
Targeted Allele Detail
Summary
Symbol: Pth1rtm1Abas
Name: parathyroid hormone 1 receptor; targeted mutation 1, Abdul B Abou-Samra
MGI ID: MGI:3687642
Gene: Pth1r  Location: Chr9:110551153-110576213 bp, - strand  Genetic Position: Chr9, 60.56 cM, cytoband F
Alliance: Pth1rtm1Abas page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113660
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Nucleotide substitutions
 
Mutation detailsA vector containing 7 serine to alanine mutations and a floxed neo-tk was inserted into the locus. The neo was subsequently removed via cre mediated recombination. (J:113660)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pth1r Mutation:  28 strains or lines available
References
Original:  J:113660 Bounoutas GS, et al., Impact of impaired receptor internalization on calcium homeostasis in knock-in mice expressing a phosphorylation-deficient parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology. 2006 Oct;147(10):4674-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory