Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rhohtm1Daw
Name:	ras homolog family member H; targeted mutation 1, David A Williams
MGI ID:	MGI:3687310
Synonyms:	Rhoh-
Gene:	Rhoh  Location: Chr5:66018556-66054043 bp, + strand  Genetic Position: Chr5, 33.8 cM, cytoband D
Alliance:	Rhohtm1Daw page

Germline Transmission:	Earliest citation of germline transmission: J:113565
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced the entire coding region, located in exon 3. Absence of protein was confirmed by immunoblot analysis. (J:113565)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rhoh Mutation:	13 strains or lines available

Original:	J:113565 Gu Y, et al., RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development. Nat Immunol. 2006 Nov;7(11):1182-1190
All:	7 reference(s)