Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Arid4atm1Alb
Name:	AT-rich interaction domain 4A; targeted mutation 1, Arthur L Beaudet
MGI ID:	MGI:3687004
Synonyms:	Arid4a-
Gene:	Arid4a  Location: Chr12:71062764-71145366 bp, + strand  Genetic Position: Chr12, 29.39 cM
Alliance:	Arid4atm1Alb page

Germline Transmission:	Earliest citation of germline transmission: J:113402
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A vector was designed to insert a lacZ and a floxed neo into the ATG in exon 1, and replacing exon 2. RT-PCR failed to detect normal transcript in mutant mice. (J:113402)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arid4a Mutation:	60 strains or lines available

Original:	J:113402 Wu MY, et al., Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain. Genes Dev. 2006 Oct 15;20(20):2859-70
All:	3 reference(s)