Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wt1tm2.1Vih
Name:	WT1 transcription factor; targeted mutation 2.1, Vicki Huff
MGI ID:	MGI:3665321
Synonyms:	Wt1delta
Gene:	Wt1  Location: Chr2:104956874-105003959 bp, + strand  Genetic Position: Chr2, 55.06 cM, cytoband E
Alliance:	Wt1tm2.1Vih page

Germline Transmission:	Earliest citation of germline transmission: J:111787
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Wt1tm2Vih in which the floxed exons 8 and 9 were deleted by using an oocyte-specific Zp3-cre transgene, resulting in a shortened protein lacking zinc fingers 2 and 3. (J:111787)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wt1 Mutation:	34 strains or lines available

Original:	J:111787 Gao F, et al., The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11987-92
All:	1 reference(s)