Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gria2tm3.1Rsp
Name:	glutamate receptor, ionotropic, AMPA2 (alpha 2); targeted mutation 3.1, Rolf Sprengel
MGI ID:	MGI:3665137
Gene:	Gria2  Location: Chr3:80588757-80710142 bp, - strand  Genetic Position: Chr3, 35.5 cM
Alliance:	Gria2tm3.1Rsp page

Germline Transmission:	Earliest citation of germline transmission: J:111689
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Gria2tm3Rsp in which the loxP flanked exon 11 is removed in the germline by crossing mice carrying this allele to mice carrying the Tg(CMV-Cre)1Cgn transgene. (J:111689)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gria2 Mutation:	75 strains or lines available

Original:	J:111689 Shimshek DR, et al., Forebrain-specific glutamate receptor B deletion impairs spatial memory but not hippocampal field long-term potentiation. J Neurosci. 2006 Aug 16;26(33):8428-40
All:	3 reference(s)