Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd8atm1.1Welm
Name:	CD8 subunit alpha; targeted mutation 1.1, Wilfried Ellmeier
MGI ID:	MGI:3664646
Synonyms:	delta2, E8ii
Gene:	Cd8a  Location: Chr6:71350411-71356155 bp, + strand  Genetic Position: Chr6, 32.14 cM, cytoband C
Alliance:	Cd8atm1.1Welm page

Germline Transmission:	Earliest citation of germline transmission: J:113136
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The neo selection cassette was removed in ES via tranfection with Cre recombinase, generating ES cells with only one loxP site. (J:113136)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd8a Mutation:	36 strains or lines available

Original:	J:113136 Ellmeier W, et al., Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression. Immunity. 2002 May;16(5):623-34
All:	4 reference(s)