Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Unc5btm1.1Dyl
Name:	unc-5 netrin receptor B; targeted mutation 1.1, Dean Y Li
MGI ID:	MGI:3654305
Gene:	Unc5b  Location: Chr10:60598373-60667360 bp, - strand  Genetic Position: Chr10, 31.52 cM, cytoband B4
Alliance:	Unc5btm1.1Dyl page

Germline Transmission:	Earliest citation of germline transmission: J:111275
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 4 to 13 were flanked with loxP sites and an FRT-flanked neomycin resistance cassette was inserted upstream of exon 4. Cre-mediated recombination removed exons 4 through 13 and the selection cassette. RT-PCR analysis confirms the absence of transcript in homozygous mice. (J:111275)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Unc5b Mutation:	61 strains or lines available

Original:	J:111275 Wilson BD, et al., Netrins promote developmental and therapeutic angiogenesis. Science. 2006 Aug 4;313(5787):640-4
All:	5 reference(s)