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Inhbctm1Zuk
Targeted Allele Detail
Summary
Symbol: Inhbctm1Zuk
Name: inhibin beta-C; targeted mutation 1, Martin M Matzuk
MGI ID: MGI:3653269
Synonyms: actbetaCm1
Gene: Inhbc  Location: Chr10:127192191-127206300 bp, - strand  Genetic Position: Chr10, 74.5 cM
Alliance: Inhbctm1Zuk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110815
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A 1.7 kb fragment including exon 2 was replaced with a PGK-hprt cassette. (J:110815)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 8 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Inhbc Mutation:  46 strains or lines available
References
Original:  J:110815 Lau AL, et al., Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration. Mol Cell Biol. 2000 Aug;20(16):6127-37
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory