Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bfsp1tm1Pgf
Name:	beaded filament structural protein 1, in lens-CP94; targeted mutation 1, Paul G FitzGerald
MGI ID:	MGI:3641549
Synonyms:	filensinko
Gene:	Bfsp1  Location: Chr2:143668448-143705093 bp, - strand  Genetic Position: Chr2, 70.89 cM, cytoband G
Alliance:	Bfsp1tm1Pgf page

Germline Transmission:	Earliest citation of germline transmission: J:109599
Parent Cell Line:	GK129 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A pgk-neo cassette replaced exon 1, promoter elements and the transcriptional start site. Northern blot confirmed absence of transcript in mutant lenses. (J:109599)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bfsp1 Mutation:	33 strains or lines available

Original:	J:109599 Alizadeh A, et al., Targeted deletion of the lens fiber cell-specific intermediate filament protein filensin. Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5252-8
All:	3 reference(s)