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Sox6tm2.2Vlf
Targeted Allele Detail
Summary
Symbol: Sox6tm2.2Vlf
Name: SRY (sex determining region Y)-box 6; targeted mutation 2.2, Veronique Lefebvre
MGI ID: MGI:3641205
Synonyms: Sox6fl-
Gene: Sox6  Location: Chr7:115070107-115638031 bp, - strand  Genetic Position: Chr7, 61.29 cM
Alliance: Sox6tm2.2Vlf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110147
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 2 was flanked by a single loxP site and an frt flanked neo followed by a single loxP site. Cre mediated recombination then removed exon 2 and the neo cassette (J:110147)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox6 Mutation:  59 strains or lines available
References
Original:  J:110147 Dumitriu B, et al., Generation of mice harboring a Sox6 conditional null allele. Genesis. 2006 May;44(5):219-24
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory