Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cpt1ctm1Mdln
Name:	carnitine palmitoyltransferase 1c; targeted mutation 1, M Daniel Lane
MGI ID:	MGI:3639356
Gene:	Cpt1c  Location: Chr7:44608796-44624275 bp, - strand  Genetic Position: Chr7, 29.07 cM, cytoband B2
Alliance:	Cpt1ctm1Mdln page

Germline Transmission:	Earliest citation of germline transmission: J:109455
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exons 1 and 2, encoding the transcription initiation site and the first transmembrane domain of the protein, with a neomycin resistance cassette. Western blot failed to detect protein in mutant brains. (J:109455)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cpt1c Mutation:	42 strains or lines available

Original:	J:109455 Wolfgang MJ, et al., The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7282-7
All:	2 reference(s)