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Dbnltm1Jwnd
Targeted Allele Detail
Summary
Symbol: Dbnltm1Jwnd
Name: drebrin-like; targeted mutation 1, Jurgen Wienands
MGI ID: MGI:3629216
Synonyms: mabp1-
Gene: Dbnl  Location: Chr11:5738488-5750962 bp, + strand  Genetic Position: Chr11, 3.87 cM
Alliance: Dbnltm1Jwnd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109363
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  BALB/c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a neomycin resistance gene in opposite orientation by homologous recombination. Protein expression was not detected in mutant brain or spleen in immunoblot analysis. (J:109363)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dbnl Mutation:  27 strains or lines available
References
Original:  J:109363 Connert S, et al., SH3P7/mAbp1 deficiency leads to tissue and behavioral abnormalities and impaired vesicle transport. EMBO J. 2006 Apr 19;25(8):1611-22
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory