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Kat6atm1Iki
Targeted Allele Detail
Summary
Symbol: Kat6atm1Iki
Name: K(lysine) acetyltransferase 6A; targeted mutation 1, Issay Kitabayashi
MGI ID: MGI:3629032
Synonyms: MOZ-
Gene: Kat6a  Location: Chr8:23349551-23433275 bp, + strand  Genetic Position: Chr8, 11.42 cM
Alliance: Kat6atm1Iki page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108699
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsInsertion of a neomycin resistance cassette into exon 2, which contains the first methionine ATG, disrupted the gene. Western blot analysis of E12.5 embryo lysates did not detect protein. (J:108699)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 39 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat6a Mutation:  67 strains or lines available
References
Original:  J:108699 Katsumoto T, et al., MOZ is essential for maintenance of hematopoietic stem cells. Genes Dev. 2006 May 15;20(10):1321-30
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory