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Nptxrtm1Mspn
Targeted Allele Detail
Summary
Symbol: Nptxrtm1Mspn
Name: neuronal pentraxin receptor; targeted mutation 1, Mark S Perin
MGI ID: MGI:3628751
Synonyms: NPR-
Gene: Nptxr  Location: Chr15:79670552-79688910 bp, - strand  Genetic Position: Chr15, 37.85 cM, cytoband E2
Alliance: Nptxrtm1Mspn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109215
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA targeting vector was designed to replace exons 2 and 3 with a neomycin resistance cassette. Northern blot failed to detect wild-type transcript in mutants. (J:109215)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nptxr Mutation:  9 strains or lines available
Notes
ES cell line was "129/SVJII derived."
References
Original:  J:109215 Bjartmar L, et al., Neuronal pentraxins mediate synaptic refinement in the developing visual system. J Neurosci. 2006 Jun 7;26(23):6269-81
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory