Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Nptx2tm1Mspn
Name:	neuronal pentraxin 2; targeted mutation 1, Mark S Perin
MGI ID:	MGI:3628749
Synonyms:	NARP-, NP2-
Gene:	Nptx2  Location: Chr5:144482712-144494288 bp, + strand  Genetic Position: Chr5, 84.58 cM, cytoband G2
Alliance:	Nptx2tm1Mspn page

Germline Transmission:	Earliest citation of germline transmission: J:109215
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exon 1, contining the signal peptide, with a neomycin resistance cassette. Northern blot failed to detect wild-type transcript in mutants. (J:109215)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nptx2 Mutation:	24 strains or lines available

Original:	J:109215 Bjartmar L, et al., Neuronal pentraxins mediate synaptic refinement in the developing visual system. J Neurosci. 2006 Jun 7;26(23):6269-81
All:	8 reference(s)