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Cdkn1btm2.1Mlf
Targeted Allele Detail
Summary
Symbol: Cdkn1btm2.1Mlf
Name: cyclin dependent kinase inhibitor 1B; targeted mutation 2.1, Matthew L Fero
MGI ID: MGI:3624666
Synonyms: p27L-
Gene: Cdkn1b  Location: Chr6:134897364-134902476 bp, + strand  Genetic Position: Chr6, 65.77 cM
Alliance: Cdkn1btm2.1Mlf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107588
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre mediated recombination of loxP sites flanking the gene resulted in the deletion of the locus in the germline. (J:107588)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkn1b Mutation:  25 strains or lines available
References
Original:  J:107588 Chien WM, et al., Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4122-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory