Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pdlim2tm1Gru
Name:	PDZ and LIM domain 2; targeted mutation 1, Michael J Grusby
MGI ID:	MGI:3623895
Gene:	Pdlim2  Location: Chr14:70401667-70415130 bp, - strand  Genetic Position: Chr14, 36.26 cM
Alliance:	Pdlim2tm1Gru page

Germline Transmission:	Earliest citation of germline transmission: J:99108
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin resistance gene was inserted into exon 2. Absence of transcript and protein was confirmed by Northern and Western blot, respectively. (J:99108)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdlim2 Mutation:	32 strains or lines available

Original:	J:99108 Tanaka T, et al., SLIM Is a Nuclear Ubiquitin E3 Ligase that Negatively Regulates STAT Signaling. Immunity. 2005 Jun;22(6):729-36
All:	5 reference(s)