Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Adipoqtm1Pesch
Name:	adiponectin, C1Q and collagen domain containing; targeted mutation 1, Philipp E Scherer
MGI ID:	MGI:3623488
Synonyms:	Adipoqtm1Pesc
Gene:	Adipoq  Location: Chr16:22965286-22976718 bp, + strand  Genetic Position: Chr16, 13.96 cM, cytoband B3-B4
Alliance:	Adipoqtm1Pesch page

Germline Transmission:	Earliest citation of germline transmission: J:107486
Parent Cell Line:	AB2.1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exon 1, exon 2 and the coding part of exon 3 with a neomycin resistance gene. Western blot failed to detect protein in mutants. (J:107486)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adipoq Mutation:	40 strains or lines available

Original:	J:107486 Nawrocki AR, et al., Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J Biol Chem. 2006 Feb 3;281(5):2654-60
All:	33 reference(s)