Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il1rl1tm1Aki
Name:	interleukin 1 receptor-like 1; targeted mutation 1, Shizuo Akira
MGI ID:	MGI:3623124
Synonyms:	ST2-, T1/ST2-
Gene:	Il1rl1  Location: Chr1:40468730-40504575 bp, + strand  Genetic Position: Chr1, 19.19 cM
Alliance:	Il1rl1tm1Aki page

Germline Transmission:	Earliest citation of germline transmission: J:58499
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace a 1280 base pair fragment encompassing exons 1 and 2, which encode amino acids 1-96 of the protein, with a neomycin resistance cassette. RT-PCR confirmed absence of transcript in mutants. (J:58499)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il1rl1 Mutation:	56 strains or lines available

Original:	J:58499 Hoshino K, et al., The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med. 1999 Nov 15;190(10):1541-8
All:	32 reference(s)