Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Ppp1r15atm1.1Ajf
Name:	protein phosphatase 1, regulatory subunit 15A; targeted mutation 1.1, Albert J Fornace, Jr
MGI ID:	MGI:3621811
Synonyms:	Gadd34-
Gene:	Ppp1r15a  Location: Chr7:45172341-45175692 bp, - strand  Genetic Position: Chr7, 29.34 cM, cytoband B2
Alliance:	Ppp1r15atm1.1Ajf page

Germline Transmission:	Earliest citation of germline transmission: J:106905
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Cre mediated recombination was used to remove exons 2 and 3 from the locus. Northern blot of mutant intestine, kidney and spleen failed to detect transcript. (J:106905)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppp1r15a Mutation:	22 strains or lines available

Original:	J:106905 Patterson AD, et al., Gadd34 requirement for normal hemoglobin synthesis. Mol Cell Biol. 2006 Mar;26(5):1644-53
All:	7 reference(s)