Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Akap1tm1Gsm
Name:	A kinase anchor protein 1; targeted mutation 1, G Stanley McKnight
MGI ID:	MGI:3620561
Gene:	Akap1  Location: Chr11:88721618-88755412 bp, - strand  Genetic Position: Chr11, 54.34 cM
Alliance:	Akap1tm1Gsm page

Germline Transmission:	Earliest citation of germline transmission: J:106320
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced exon 2, which encodes the majority of the protein in all splice variants. Western blot confirmed that all variants were absent in mutant tissues including ovary. (J:106320)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Akap1 Mutation:	64 strains or lines available

Original:	J:106320 Newhall KJ, et al., Dynamic anchoring of PKA is essential during oocyte maturation. Curr Biol. 2006 Feb 7;16(3):321-7
All:	7 reference(s)