Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Naip1tm1Aem
Name:	NLR family, apoptosis inhibitory protein 1; targeted mutation 1, Alex E MacKenzie
MGI ID:	MGI:3620316
Synonyms:	Birc1a-, Naip1-
Gene:	Naip1  Location: Chr13:100544272-100589372 bp, - strand  Genetic Position: Chr13, 53.18 cM, cytoband D1-D3
Alliance:	Naip1tm1Aem page

Germline Transmission:	Earliest citation of germline transmission: J:60925
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: An IRES-lacZ and PGK-neo was inserted to replace exons 2 and 3. RT-PCR failed to detect transcript in mutants. (J:60925)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Naip1 Mutation:	78 strains or lines available

Original:	J:60925 Holcik M, et al., The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2286-90
All:	2 reference(s)